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导师简介

叶春林

2017/04/25 19:21:22 次浏览 分类:导师简介

   

    叶春林,男,博士,教授,硕士生导师。1990年7月毕业于华东化工学院(现华东理工大学)化学工程学系,获学士学位;2002年3月毕业于浙江大学化学工程与生物工程学系,获硕士学位;2005年3月毕业于华东理工大学生物工程学院,获博士学位;2005年4月进入浙江科技学院生物与化学工程学系任教。2014年5月至2015年5月,作为访问学者在美国耶鲁大学(Yale University)医学院学术交流。
主要从事抗肿瘤、抗心脑血管疾病活性成分的发现与利用、肿瘤的靶向治疗、活性成分抗肿瘤的作用靶点、细胞内信号转导通路等领域的科学研究工作。
主要项目和成果

项目:
1. 浙江省科技厅科技计划项目“洋葱含硫生物活性物超临界CO2提取及微囊制备应用研究”(2008C32024) 主持
2. 浙江省自然科学基金课题“水翁花诱导肝癌细胞凋亡的活性成分及分子机制研究”(LY12C02002)主持
3. 浙江省自然科学基金课题“三叶青抗肝癌的物质基础及作用机理研究”(LY17C020003)主持
  
论文:
1. Chun-Lin Ye, Yan-Hua Lu, Dong-Zhi Wei. Flavonoids From Cleistocalyx Operculatus. Phytochemistry 2004; 65: 445-447.
2. Chun-Lin Ye, Jian-Wen Liu, Dong-Zhi Wei, Yan-Hua Lu, Feng Qian. In Vitro Anti-Tumor Activity Of 2',4'-Dihydroxy-6'-Methoxy-3',5'-Dimethylchalcone Against Six Established Human Cancer Cell Lines. Pharmacological Research 2004; 50: 505-510.
3. Chun-Lin Ye, Jian-Wen Liu, Dong-Zhi Wei, Yan-Hua Lu, Feng Qian. In Vivo Anti-Tumor Activity By 2',4'-Dihydroxy-6'-Methoxy-3',5'-Dimethylchalcone In A Solid Human Carcinoma Xenograft Model. Cancer Chemotherapy And Pharmacology 2005; 55: 447-452.
4. Chun-Lin Ye, Yan-Hua Lu, Xiao-Dun Li, Dong-Zhi Wei. HPLC Analysis Of Bioactive Chalcone And Triterpene In The Buds Of Cleistocalyx Operculatus. South African Journal Of Botany 2005; 71: 312-315.
5. Chun-Lin Ye, Feng Qian, Dong-Zhi Wei, Yan-Hua Lu, Jian-Wen Liu. Induction Of Apoptosis In K562 Human Leukemia Cells By 2',4'-Dihydroxy-6'-Methoxy-3',5'-Dimethylchalcone. Leukemia Research 2005; 29: 887-892.
6. Chun-Lin Ye, Yu Liu, Dong-Zhi Wei. Antioxidant And Anticancer Activities Of 3′-Formyl-4′,6′-Dihydroxy-2′-Methoxy-5′-Methylchalcone And (2S)-8-Formyl-5-Hydroxy-7-Methoxy-6-Methylflavanone. Journal Of Pharmacy And Pharmacology 2007; 59: 553-559.
7. Chun-Lin Ye, Cheng-Jun Jiang. Optimization Of Extraction Process Of Crude Polysaccharides From Plantago Asiatica L. By Response Surface Methodology. Carbohydrate Polymers 2011; 84: 495-502.
8.Chun-Lin Ye, Wei-Lian Hu, De-Hui Dai. Extraction Of Polysaccharides And The Antioxidant Activity From The Seeds Of Plantago Asiatica L. International Journal Of Biological Macromolecules 2011; 49: 466-470.
9. Chun-Lin Ye, Yi-Feng Lai. Supercritical CO2 Extraction Optimization Of Onion Oil Using Response Surface Methodology. Chemical Engineering & Technology 2012; 35: 646-652.
10. Chun-Lin Ye, Qi Huang. Extraction Of Polysaccharides From Herbal Scutellaria Barbata D. Don (Ban-Zhi-Lian) And Their Antioxidant Activity. Carbohydrate Polymers 2012; 89: 1131-1137.
11. Chun-Lin Ye, De-Hui Dai, Wei-Lian Hu. Antimicrobial And Antioxidant Activities Of The Essential Oil From Onion (Allium Cepa L.). Food Control 2013; 30: 48-53.
12. Chun-Lin Ye, Xuan-Gan Liu, Qi Huang. Antioxidant Activity And Protection Of Human Umbilical Vein Endothelial Cells From Hydrogen Peroxide-Induced Injury By DMC, A Chalcone From Buds Of Cleistocalyx Operculatus. South African Journal Of Botany 2013; 86: 36-40.
13. Chun-Lin Ye, Xuan-Gan Liu, Qi Huang, Xian-Liang Zhao. Induction Of Apoptosis In Human Hepatoma SMMC-7721 Cells Using 2',4'-Dihydroxy-6'-Methoxy-3',5'-Dimethylchalcone, A Chalcone From Buds Of Cleistocalyx Operculatus. Food Science And Biotechnology 2013; 22: 1421-1427.
14. Chun-Lin Ye, Yi-Feng Lai. Optimization Of Extraction Process And Antioxidant Activity Of Polysaccharides From Leaves Of Artemisia Argyi Levl. Et Vant. Journal Of Food Processing And Preservation 2015; 39: 1309-1317.
15. Chun-Lin Ye, Xuan-Gan Liu. Extraction Of Flavonoids From Tetrastigma Hemsleyanum Diels Et Gilg And Their Antioxidant Activity. Journal Of Food Processing And Preservation 2015; 39: 2197-2205.
16. Chun-Lin Ye, Yi-Feng Lai. 2′,4′-Dihydroxy-6′-Methoxy-3′,5′-Dimethylchalcone, From Buds Of Cleistocalyx Operculatus, Induces Apoptosis In Human Hepatoma SMMC-7721 Cells Through A Reactive Oxygen Species-Dependent Mechanism. Cytotechnology 2016; 68: 331-341.



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